Posted: September 5th, 2022

The relation between pharmacology, pharmacokinetics, and pharmacodynamics

The relation between pharmacology, pharmacokinetics, and pharmacodynamics to pathophysiology
Pathophysiology is the study of any abnormal changes in the human body that are caused by a disease. Pathophysiology is a major course in nursing because it helps in building a strong foundation and allows the nurse to perform their daily responsibilities, including ordering diagnostic tests, prescribing and administering medication, preparing treatment plans, and developing preventive measures for infectious diseases. The ability to recognize and associate specific symptoms with a condition enables the nurse to provide effective and quality health care services. Pathophysiology also draws knowledge from other prerequisite subjects, including pharmacology, pharmacokinetics, and pharmacodynamics.
Pharmacology and pathophysiology
Pharmacology is the study of drug action in the body. The fundamentals of pharmacology include drug classification, drug action, drug development, and the absorption and metabolism process of the drugs. Therefore, while pathophysiology seeks to understand human diseases, pharmacology allows the right treatment of various disorders, starting from minor conditions like pain, inflammation, and neoplasia to more complicated illnesses. Nurses with a robust and integrated understanding of diseases and pharmacology can provide quality care.
Pharmacokinetics and Pathophysiology
Pharmacokinetics is the study of the movement of drugs through absorption, metabolism, and excretion. The main goal of pharmacokinetics is to control the toxicity of drug therapy to ensure that each patient receives effective drug management. Pathophysiological changes that are common in chronic illnesses have a direct impact on pharmacokinetics. Efficient dosing, even when changes occur, is crucial for survival. Sometimes, multiple conditions can exist simultaneously, and this impacts pharmacokinetics, complicating the right concentrations that will be adequate for treatment. In such situations, the possibilities of overdosing or underdoing are present. The task of establishing the concentration of serums is quite complex, and therapeutic drug monitoring and drug therapy are used.
Pharmacodynamics and Pathophysiology
Pharmacodynamics is the study of the biochemical and physiological effects of drugs and their mechanisms of action on the body. Drugs work by interacting with receptors in the body to produce a biological response. A major group of drug receptors contains proteins that act as receptors. These receptors are known as physiological receptors, and most drugs act on them due to their ability to recognize and respond to various chemicals in the drugs. The response of these receptors may be influenced by multiple factors such as the concentration of the drug, multiple drugs competing for the same receptor, the functional state of a specific receptor, and various pathophysiological factors. Understanding pharmacodynamics provides a basis for the rational therapeutic use of different drugs for different conditions.

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